Formulation Spec Sheet • Ref. NIA-10

Niacinamide zinc pore serum for sebum regulation and lipid tolerance.

10.0% pharmaceutical-grade nicotinamide paired with 1.0% zinc pyrrolidone carboxylic acid to stabilize sebaceous gland output, reinforce follicular walls, and suppress redness.

Unit Price: 28–46 USD / unit Available Volumes: 30ml / 60ml Active pH: 5.8 ± 0.2 Dispensary: 224 SW 1st Ave, Portland
Verified Dispensary Price
28–46 USD per unit
30ml frosted treatment pump ($28) • 60ml value bottle ($46)
Confirmed by Portland inventory receipts.

Sebum balancing without drying the surrounding stratum corneum.

When clients present with enlarged pores and stubborn T-zone shine, conventional over-the-counter advice urges aggressive drying astringents, alcohol toners, or heavy foaming clays. This treatment creates an immediate rebound effect: stripped epidermal lipids trigger the sebaceous gland to pump out even more sebum to coat the cracked horn cells.

Our 10% Niacinamide & 1% Zinc PCA formulation interrupts this vicious cycle. Niacinamide acts as a critical precursor to NAD+/NADH coenzymes, stimulating internal ceramide synthesis while regulating follicular lipid synthesis. Zinc PCA provides organic mineral regulation of 5-alpha reductase without drying surrounding skin tissue, while centella asiatica leaf water cools inflammatory erythema.

Formulation Architecture & Mechanism

  • 10.0% Purified Nicotinamide High-purity grade guaranteed under 100 parts per million of free nicotinic acid, preventing the sudden hot redness flush common to poorly synthesized commercial niacinamide serums.
  • 1.0% Zinc PCA Organic zinc salt bound to pyrrolidone carboxylic acid—a primary component of the skin's natural moisturizing factor (NMF). Provides targeted antimicrobial activity and reduces lipid oxidation.
  • Centella Asiatica Hydrosol Replaces standard demineralized water to provide natural triterpenoid saponins that dampen inflammatory signaling pathways in stressed sebaceous follicles.
  • Sodium Hyaluronate (100kDa) Delivers targeted intermediate hydration to keep follicular pore margins supple, preventing cellular clogging.

Sequential Application Protocol

Step 1: Application Order Morning or Evening

Dispense 2 pumps onto clean, dry fingertips. Apply across the central T-zone, nose, and chin, then smooth outward over the cheeks.

Step 2: Molecular Absorption Window 60 Seconds

Allow the water-gel texture to absorb completely. The formula sets with a clean, dry, non-tacky finish without polymer film formation.

Step 3: Pairing with Moisture Barrier Next Step

In the morning, follow with our Zinc Oxide Non-Nano SPF 50 Fluid. In the evening, follow with Centella Squalane Soothing Cream Gel.

Formulation Tradeoffs & Actives Conflicts

Niacinamide operates at an optimal pH between 5.5 and 6.5. We explicitly advise clients against layering this serum at the exact same minute as raw, unbuffered L-Ascorbic Acid (pure vitamin C) formulated below pH 3.5. Layering them directly on top of each other can cause temporary complexation and minor skin prickling.

Who this is not for: Clients with severe barrier breakdown manifesting as active eczema or raw open cracks should first spend two weeks restoring basic lipid levels with our Ceramide Complex 3:1:1 Cream before introducing 10% active niacinamide.

Studio Procurement

Inquire regarding current Portland dispensary stock.

We dispense our 10% Niacinamide & 1% Zinc PCA Refining Serum in 30ml ($28 USD) and 60ml ($46 USD) frosted treatment pump bottles. Fill out this brief intake form to reserve a unit or schedule an appointment with Irina Petrova.

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Sibling Formulations to Compare

For deep dehydration lines, view our Hyaluronic Acid & Provitamin B5 Serum ($34–$58 USD). For pore purification without stripping, see our French Illite & Montmorillonite Clay Mask ($24–$48 USD).